Melatonin may reduce anxiety before surgery by promoting a calming effect on the central nervous system. Studies suggest it can be as effective as some prescription medications for pre-operative anxiety.
Melatonin, a hormone primarily secreted by the pineal gland, plays a crucial role in regulating the sleep-wake cycle. Its potential to reduce anxiety before surgery is thought to stem from its ability to modulate GABAergic neurotransmission, promoting a calming effect on the central nervous system. This can lead to decreased feelings of apprehension and stress associated with upcoming surgical procedures.
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