SAMe supplementation may improve mood and reduce symptoms of depression by affecting neurotransmitter levels. It is often used as an adjunct to antidepressant medications.
SAMe (S-Adenosylmethionine) is a naturally occurring compound in the body involved in various biochemical reactions, including neurotransmitter synthesis. Supplementation with SAMe may improve mood and alleviate symptoms of depression by influencing the levels of neurotransmitters such as serotonin, dopamine, and norepinephrine. It is thought to act as a methyl donor and contribute to the synthesis and regulation of these neurotransmitters. While SAMe may offer benefits, it's often considered as an adjunct therapy rather than a primary treatment for depression and should be used under medical supervision, especially in conjunction with antidepressant medications.