MCC aids in tablet disintegration within the digestive tract by absorbing water and swelling, leading to quicker release and absorption of active pharmaceutical ingredients. This improves the bioavailability of medications.
Microcrystalline cellulose (MCC) acts as a disintegrant in pharmaceutical tablets. When a tablet containing MCC is ingested, MCC absorbs water, causing it to swell. This swelling action breaks the tablet apart into smaller particles, increasing the surface area exposed to digestive fluids. This enhanced surface area facilitates the dissolution of the active pharmaceutical ingredients (APIs), allowing them to be absorbed into the bloodstream more readily. The overall effect is improved bioavailability and therapeutic efficacy of the medication.