High-dose riboflavin can improve mitochondrial function, potentially stabilizing neuronal excitability and reducing the frequency and severity of migraine headaches. This effect is believed to be achieved through optimization of cellular energy production.
Riboflavin, also known as vitamin B2, is believed to improve mitochondrial function, which can be impaired in individuals experiencing migraines. By optimizing cellular energy production, riboflavin may help stabilize neuronal excitability and reduce the likelihood of migraine attacks. High doses are typically required to achieve this effect.