Butterbur

Inside Body
Inside: Harmless

Butterbur (Petasites hybridus) is a plant used traditionally for its medicinal properties. It contains petasin and isopetasin, believed to be the active compounds responsible for its effects. It is of...

Butterbur (Petasites hybridus) is a plant used traditionally for its medicinal properties. It contains petasin and isopetasin, believed to be the active compounds responsible for its effects. It is often used to manage migraines, allergic rhinitis, and asthma. However, it is important to use PA-free (pyrrolizidine alkaloids-free) extracts to avoid liver toxicity.

Key Information

Inside Body Harmful Score

Harmless

Common Dosage

50-150mg twice daily of PA-free extract

Source Type

natural

Production Process

Butterbur extracts are derived from the root or leaves of the Petasites hybridus plant. The plant material is typically dried and extracted using solvents. A crucial step involves removing pyrrolizidine alkaloids (PAs) to create a PA-free extract, as PAs are hepatotoxic.

Use Type

Inside Body

Potential Benefits

Migraine prevention aims to decrease the frequency, severity, and duration of migraines through lifestyle changes, nutrition, and/or medication. The goal is to stabilize neurological function and reduce reliance on acute treatments, thereby improving quality of life.

3/5

Possible Side Effects

Headache

Headache is pain in the head ranging from mild to severe, potentially with nausea, light/sound sensitivity, or dizziness. It can be caused by tension, dehydration, stress, or medication side effects, and persistent headaches require medical evaluation.

low
Fatigue

Fatigue is a common symptom of perceived lack of physical and/or mental energy interfering with daily activities. It can be caused by various factors and manifests differently in intensity and duration.

low
Allergic Reactions

Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.

medium
Liver toxicity

High doses of green tea extract, especially in concentrated forms, can rarely cause liver toxicity. Individuals with pre-existing liver conditions should exercise caution.

medium
Gastrointestinal discomfort

High doses of MK-7 may cause mild gastrointestinal discomfort such as nausea or upset stomach. Symptoms are typically mild and transient.

low

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