About Gluconolactone
Gluconolactone (PHA) is a polyhydroxy acid derived from glucose oxidation, widely used in skincare for its gentle exfoliating, hydrating, and antioxidant effects. It's considered a suitable alternative to AHAs, especially for sensitive skin. While generally safe, mild skin irritation and increased sun sensitivity are potential side effects. It is also used as a food additive functioning as a sequestrant, acidulant and leavening agent. Oral consumption dosages for specific health benefits are not well-defined, but topical application is common in varying concentrations depending on the product formulation.
Key Information
Compare All Forms
Compare different forms of Gluconolactone by bioavailability, conversion rates, and active ingredient content:
| Form | Tier | Steps |
Gluconolactone (mg) |
Bioavailability | Action |
|---|---|---|---|---|---|
|
Gluconolactone (PHA)
Gluconolactone (PHA) gently exfoliates, hydrates, and provid... |
Tier 2 | 1 | — | Moderate bioavailability form. Reliable form that works well but requires 1-2 step conversions by the body. Good balance of cost and effectiveness. | View → |
Scientific Evidence
Studies on gluconolactone's use in skincare, including its efficacy in exfoliation, hydration, and antioxidant protection, as well as its lower irritancy compared to AHAs. Research on its role as a food additive. Further clinical trials are needed to establish the effects of oral consumption.