About Trimethylglycine
Trimethylglycine (TMG), also known as betaine, is a naturally occurring compound primarily extracted from sugar beets. It functions as a methyl donor, crucial for processes such as homocysteine metabolism, creatine synthesis, and liver function. Supplementation with TMG is often used to support cardiovascular health by lowering homocysteine levels and is being researched for its potential benefits in athletic performance and liver health. Common dosages range from 500-6000mg daily. While generally safe, gastrointestinal distress is possible, and rarely, it can exacerbate or trigger trimethylaminuria.
Key Information
Compare All Forms
Compare different forms of Trimethylglycine by bioavailability, conversion rates, and active ingredient content:
| Form | Tier | Steps |
Trimethylglycine (mg) |
Bioavailability | Action |
|---|---|---|---|---|---|
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Trimethylglycine (TMG)
Trimethylglycine (TMG), also known as betaine, is used to su... |
Tier 1 | 0 | — | High bioavailability form. Body-ready, bypasses conversion steps. Maximum absorption, lowest waste. | View → |
Scientific Evidence
Studies on homocysteine reduction, athletic performance (e.g., improvement in power output), and liver function (e.g., reducing fat accumulation in the liver). Search PubMed and Google Scholar for 'Trimethylglycine' or 'Betaine' and relevant keywords (homocysteine, athletic performance, liver health).