Citicoline supports brain health and function, potentially enhancing cognitive function and aiding in stroke recovery.
Citicoline is a naturally occurring brain chemical and also a dietary supplement that supports brain health by acting as a precursor to phosphatidylcholine, a vital component of cell membranes. It's used to enhance cognitive function, potentially aid stroke recovery, and potentially benefit individuals with age-related cognitive decline and glaucoma. While generally well-tolerated, potential side effects include headache, insomnia, and gastrointestinal distress.
Key Information
Inside Body Harmful Score
Common Dosage
250-2000mg daily, often divided into two doses
Source Type
natural
Production Process
Citicoline can be derived naturally or produced synthetically. In the body, it is formed during the biosynthesis of phosphatidylcholine. As a supplement, it's often produced via chemical synthesis using cytidine and choline.
Use Type
Inside BodyPotential Benefits
Cognitive enhancement improves mental performance by boosting memory, attention, and processing speed. It works by promoting neuronal health and protecting against cognitive decline.
Alpha-GPC may improve stroke recovery by increasing acetylcholine levels, enhancing neuronal plasticity, and aiding in the repair of damaged neuronal structures. It potentially facilitates the brain's ability to reorganize and form new connections after a stroke.
Citicoline may enhance memory and cognitive function in individuals with age-related cognitive decline and early Alzheimer's by supporting neurotransmitter levels and neuronal health. It potentially improves brain function in affected individuals.
Citicoline protects brain cells by supporting neuronal membrane repair, enhancing cholinergic neurotransmission, and reducing oxidative stress and excitotoxicity. This helps to maintain and improve overall neuronal health.
Citicoline may slow age-related cognitive decline by supporting brain cell health and neurotransmission. This could improve memory, learning, and overall cognitive abilities.
Citicoline may protect retinal ganglion cells, potentially benefiting individuals with glaucoma by preserving visual function and slowing disease progression. It's thought to work through neuroprotective mechanisms.
Possible Side Effects
Insomnia is a sleep disorder involving difficulty falling or staying asleep, leading to non-restorative sleep. It can be triggered by various factors and can result in daytime fatigue and impaired cognitive function.
Headache is pain in the head ranging from mild to severe, potentially with nausea, light/sound sensitivity, or dizziness. It can be caused by tension, dehydration, stress, or medication side effects, and persistent headaches require medical evaluation.
Gastrointestinal issues include nausea, diarrhea, abdominal discomfort, and vomiting, potentially stemming from altered gut motility, microbiota changes, or irritation. While often mild, persistent symptoms necessitate evaluation, and contributing factors like pre-existing conditions should be considered.
Scientific Evidence
Several studies have investigated citicoline's effects on cognitive function, stroke recovery, and glaucoma. Key studies include those evaluating its impact on memory, attention, and neurological outcomes after stroke. Research has explored its mechanism of action in protecting neurons and enhancing neurotransmitter function. Further research is ongoing to fully elucidate its long-term benefits and optimal usage.
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