Creatine Ethyl Ester (CEE) is a creatine derivative with an added ethyl ester group, initially marketed for supposedly superior absorption. However, research demonstrates that CEE is unstable in the d...
Creatine Ethyl Ester (CEE) is a creatine derivative with an added ethyl ester group, initially marketed for supposedly superior absorption. However, research demonstrates that CEE is unstable in the digestive system, rapidly degrading into creatinine and exhibiting lower bioavailability than creatine monohydrate. Consequently, CEE is considered less effective for increasing muscle creatine stores and improving athletic performance. Moreover, some studies suggest a higher potential for side effects compared to creatine monohydrate, making it a less desirable creatine form.
Key Information
Inside Body Harmful Score
Common Dosage
Dosage recommendations vary, but typically follow similar ranges to creatine monohydrate (e.g., 3-5g daily). However, due to its lower bioavailability and potential for breakdown, the effectiveness of these dosages is questionable.
Source Type
synthetic
Production Process
Creatine Ethyl Ester is produced by esterifying creatine with ethanol.
Use Type
Inside BodyPotential Benefits
Esterification of creatine aimed to enhance absorption and muscle creatine storage, but studies haven't shown superiority over creatine monohydrate. Creatine esters do not appear to improve muscle uptake or performance beyond what is achievable with creatine monohydrate.
Possible Side Effects
Stomach upset, diarrhea, or cramping may occur in some individuals.
Topical caffeine can dehydrate the skin due to its diuretic effect, leading to dryness and irritation. Counteracting this effect with moisturizers is crucial.
Elevated creatinine levels indicate increased creatinine in the blood, potentially interfering with kidney function tests. It may suggest impaired kidney function, but can also occur in healthy individuals due to other factors.
Scientific Evidence
Studies comparing CEE to creatine monohydrate have consistently shown CEE's inferiority in terms of muscle creatine uptake and overall effectiveness. Search for studies comparing Creatine Ethyl Ester vs Creatine Monohydrate effectiveness and stability.
User Reviews
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