DHEA

Inside Body
Inside: Harmless

Dehydroepiandrosterone (DHEA) is a naturally occurring hormone produced by the adrenal glands, gonads, and brain. It serves as a precursor to several sex hormones, including testosterone and estrogen....

Dehydroepiandrosterone (DHEA) is a naturally occurring hormone produced by the adrenal glands, gonads, and brain. It serves as a precursor to several sex hormones, including testosterone and estrogen. DHEA levels naturally decline with age. As a supplement, DHEA is often used to address age-related decline, improve physical performance, and treat certain medical conditions.

Key Information

Inside Body Harmful Score

Harmless

Common Dosage

25-50mg daily

Source Type

natural

Production Process

DHEA is extracted from wild yam or soy and then chemically synthesized to match the human hormone. Microbial fermentation is also used.

Use Type

Inside Body

Potential Benefits

DHEA supplementation may improve bone mineral density, especially in older adults and particularly in women, potentially reducing osteoporosis risk. This is thought to be due to DHEA's conversion into estrogen and testosterone, which are important for bone health.

2/5

DHEA supplementation may offer antidepressant effects, particularly in individuals with lower DHEA levels, potentially by influencing neurotransmitter activity. The effects are thought to be linked to the modulation of GABAergic and glutamatergic neurotransmission.

2/5

DHEA may help reduce disease activity and improve quality of life in individuals with SLE by modulating the immune system and reducing inflammation. It potentially alleviates fatigue and musculoskeletal pain.

3/5

Possible Side Effects

Acne

Acne is a common skin condition involving comedones, papules, pustules, and nodules caused by factors like excess sebum, clogged follicles, inflammation, and bacteria. Severity ranges from mild breakouts to severe inflammation and scarring.

low
Mood Changes

Mood changes involve fluctuations in emotional state, ranging from irritability to euphoria, impacting daily life and well-being. These changes may be caused by physiological or psychological factors, necessitating careful evaluation.

medium
low

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