Gluconolactone

Outside Body
Outside: Harmless

Gluconolactone is a polyhydroxy acid (PHA) that acts as a humectant, antioxidant, and mild exfoliant. It is formed by the oxidation of glucose and is naturally found in honey, fruit juices, and wine....

Gluconolactone is a polyhydroxy acid (PHA) that acts as a humectant, antioxidant, and mild exfoliant. It is formed by the oxidation of glucose and is naturally found in honey, fruit juices, and wine. It is often used in skincare products for its moisturizing and skin-smoothing properties. As a food additive, it functions as an acidity regulator, leavening agent, and sequestrant. It is generally considered safe for topical and oral use.

Key Information

Outside Body Harmful Score

Harmless

Common Dosage

Skincare: Varies by product concentration. Food additive: As per food regulations.

Source Type

hybrid

Production Process

Produced by the fermentation of glucose or by the chemical oxidation of glucose.

Use Type

Outside Body

Potential Benefits

Gluconolactone is a humectant that attracts and binds water to the skin, providing hydration. It also acts as a mild exfoliant for smoother skin texture.

3/5

PHAs strengthen the skin barrier by promoting ceramide synthesis. This enhances skin hydration and protection against external irritants.

3/5

Possible Side Effects

Skin irritation

Topical application can cause skin irritation, manifesting as redness, itching, and other symptoms. Severity varies based on individual factors and exposure, usually resolving after stopping use.

low
Photosensitivity

Photosensitivity is an increased sensitivity to UV radiation, leading to sunburn, rash, or blistering. Reactions can be phototoxic or photoallergic, with symptoms ranging from mild redness to severe blistering and potentially increasing skin cancer risk with prolonged exposure.

low

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