Methylglyoxal (MGO)

Outside Body
Outside: Harmless

Methylglyoxal (MGO) is a naturally occurring compound found in various foods and is a key component in the antibacterial activity of Manuka honey. However, it is also a reactive dicarbonyl compound fo...

Methylglyoxal (MGO) is a naturally occurring compound found in various foods and is a key component in the antibacterial activity of Manuka honey. However, it is also a reactive dicarbonyl compound formed as a byproduct of glycolysis and other metabolic processes. In high concentrations, MGO can contribute to oxidative stress and the formation of advanced glycation end products (AGEs), which are implicated in various age-related diseases.

Key Information

Outside Body Harmful Score

Harmless

Common Dosage

No established safe or effective supplemental dosage. MGO intake from food varies greatly.

Source Type

natural

Production Process

MGO can be produced synthetically through various chemical reactions. It is also naturally produced in vivo during glycolysis and non-enzymatic reactions.

Use Type

Outside Body

Potential Benefits

Manuka honey possesses antibacterial properties thanks to its MGO content, which hinders bacterial growth by disrupting cellular functions. It is effective against bacteria like Staphylococcus aureus and Escherichia coli.

3/5

Possible Side Effects

medium
medium

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