Pyrroloquinoline quinone (PQQ) is a naturally occurring, vitamin-like compound with significant antioxidant properties. It plays a role in mitochondrial biogenesis, potentially enhancing cellular ener...
Pyrroloquinoline quinone (PQQ) is a naturally occurring, vitamin-like compound with significant antioxidant properties. It plays a role in mitochondrial biogenesis, potentially enhancing cellular energy production and overall health. Research suggests benefits in areas such as cognitive function, cardiovascular health, and nerve growth. While generally considered safe at recommended dosages (20-40mg daily), mild side effects like headache or insomnia may occur in some individuals. Its mechanism of action involves stimulating mitochondrial biogenesis, reducing oxidative stress, and promoting nerve growth factor production.
Key Information
Inside Body Harmful Score
Common Dosage
20-40mg daily
Source Type
natural
Production Process
PQQ is naturally occurring and can be extracted from various foods and bacteria. It can also be synthesized in a laboratory setting.
Use Type
Inside BodyPotential Benefits
Enhances mental processes involved in thinking, learning, and remembering, including memory, attention, focus, and processing speed. Benefits range from improved mental clarity to significant enhancements in cognitive abilities, especially in those with cognitive decline.
Cardiovascular health ensures efficient blood circulation by maintaining healthy heart and blood vessels. Benefits include reduced risk of heart disease and stroke through improved blood flow and heart function.
Mitochondrial health enhancement optimizes mitochondrial function to boost cellular energy, reduce fatigue, and support healthy aging. It involves protecting mitochondria, providing essential nutrients, and promoting mitochondrial biogenesis.
Aged garlic extract acts as an antioxidant by neutralizing free radicals, protecting cells from damage and potentially reducing the risk of chronic diseases. The allicin-derived metabolites are the active components.
PQQ is believed to stimulate mitochondrial biogenesis, increasing the number of mitochondria in cells. This can lead to improved cellular energy production and enhanced metabolic function.
PQQ potentially promotes nerve growth factor (NGF) production, essential for nerve cell health and survival. This may lead to improved neuronal function and regeneration.
Possible Side Effects
Insomnia is a sleep disorder involving difficulty falling or staying asleep, leading to non-restorative sleep. It can be triggered by various factors and can result in daytime fatigue and impaired cognitive function.
Headache is pain in the head ranging from mild to severe, potentially with nausea, light/sound sensitivity, or dizziness. It can be caused by tension, dehydration, stress, or medication side effects, and persistent headaches require medical evaluation.
Hypothetically, this substance can cause mild skin irritation with redness, itching, and burning at the application site, resolving on its own.
Upper abdominal discomfort is a mild discomfort or nausea felt in the upper abdomen. It can present as bloating, fullness, or mild pain.
Scientific Evidence
Key scientific sources include studies published in journals like 'Biochemical and Biophysical Research Communications', 'Journal of Nutritional Biochemistry', and 'Rejuvenation Research'. Studies often investigate PQQ's effects on mitochondrial function, cognitive performance, and biomarkers of oxidative stress and inflammation. Further large-scale clinical trials are needed to confirm these preliminary findings and establish optimal dosages and safety profiles.
User Reviews
Share your experience with this ingredient
Log in to write a reviewNo reviews yet. Be the first to share your experience!