Resveratrol, found in grapes, has antioxidant and anti-inflammatory properties potentially benefiting cardiovascular health, but may cause distress.
Resveratrol is a naturally occurring polyphenol found in grapes, berries, and other plants. It is known for its antioxidant, anti-inflammatory, and potential cardiovascular benefits. While generally safe, it may cause gastrointestinal distress in some individuals and can interact with certain medications. Research is ongoing to explore its potential roles in preventing chronic diseases, improving cognitive function, and fighting cancer.
Key Information
Inside Body Harmful Score
Common Dosage
250-500mg daily
Source Type
natural
Production Process
Resveratrol is extracted from natural sources such as grapes (especially red grape skins), berries (blueberries, cranberries), peanuts, and Japanese knotweed (Polygonum cuspidatum). Extraction methods vary but commonly involve solvents. Synthetic production is also possible, though less common for supplements.
Use Type
Inside BodyPotential Benefits
Cardiovascular health ensures efficient blood circulation by maintaining healthy heart and blood vessels. Benefits include reduced risk of heart disease and stroke through improved blood flow and heart function.
Reduces inflammation by inhibiting inflammatory pathways and the production of inflammatory molecules, thereby alleviating symptoms and protecting against tissue damage. This benefit helps modulate inflammatory responses and promote resolution.
Neuroprotective effects safeguard brain cells from damage, potentially improving cognitive function and preventing neurodegenerative diseases. This is achieved through antioxidant, anti-inflammatory, and neuronal survival support mechanisms.
Aged garlic extract acts as an antioxidant by neutralizing free radicals, protecting cells from damage and potentially reducing the risk of chronic diseases. The allicin-derived metabolites are the active components.
Resveratrol exhibits anti-cancer effects by inhibiting cancer cell growth, promoting apoptosis, and preventing angiogenesis in vitro and in animal studies. Further research is needed to confirm its efficacy in human cancer treatment.
Possible Side Effects
Gastrointestinal distress involves digestive discomfort like bloating, diarrhea, cramps, nausea, and vomiting. Severity varies based on individual factors and can be triggered by irritation or inflammation of the digestive tract.
Drug interactions can alter a drug's effectiveness, leading to either increased risk of blood clots or bleeding, particularly with anticoagulants. Monitoring is essential to manage these interactions.
Puerarin, due to its estrogen-like effects, can cause hormonal imbalances, especially at high doses or with prolonged use. This may lead to menstrual irregularities or other hormone-related problems.
Scientific Evidence
Key scientific sources and studies include research published in journals such as the American Journal of Clinical Nutrition, the Journal of Nutritional Biochemistry, and the Annals of the New York Academy of Sciences. Specific studies have examined its effects on cardiovascular health, inflammation, cancer cell growth, and neuroprotection. Evidence ranges from in vitro and animal studies to human clinical trials, with varying degrees of rigor and sample sizes.
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