Vitamin B12 (methylcobalamin) is vital for nerve function, brain health, and red blood cell production, as it's a readily used form.
Methylcobalamin is a highly bioavailable and neurologically active form of Vitamin B12, essential for nerve function, brain health, red blood cell production, and energy metabolism. It plays a critical role in DNA synthesis and neurological function, making it crucial for overall health and well-being. Unlike cyanocobalamin, methylcobalamin is readily usable by the body without conversion. Supplementation may improve conditions like neuropathy and support cognitive functions.
Key Information
Inside Body Harmful Score
Common Dosage
500-5000 mcg daily
Source Type
synthetic
Production Process
Methylcobalamin is typically synthesized through a fermentation process using specific microorganisms that produce cobalamins. The final product is then refined and purified to isolate methylcobalamin.
Use Type
Inside BodyPotential Benefits
Enhances mental processes involved in thinking, learning, and remembering, including memory, attention, focus, and processing speed. Benefits range from improved mental clarity to significant enhancements in cognitive abilities, especially in those with cognitive decline.
This benefit enhances physical vitality and mental alertness by improving energy levels, reducing fatigue, and improving cognitive function. It contributes to overall health, productivity, and the ability to perform daily tasks effectively.
This benefit enhances and maintains optimal brain function, including cognitive abilities, memory, focus, learning, and mood regulation. It provides protection against age-related cognitive decline by supporting neuronal health and cerebral blood flow.
Supports healthy nerve function in both the central and peripheral nervous systems. This includes nerve signal transmission, nerve cell protection, and nerve regeneration.
Energy metabolism is the process of converting nutrients into energy (ATP), essential for bodily functions. Efficient energy metabolism supports physical activity, reduces fatigue, and contributes to overall health, while dysfunction can lead to metabolic disorders.
Supports nerve health and function in both the peripheral and central nervous systems by promoting regeneration, reducing pain and inflammation, improving signal transmission, and protecting against damage. This contributes to optimal sensory perception, motor control, and neurological function.
Red blood cell production is essential for oxygen transport, relying on iron, vitamin B12, folate, and erythropoietin. Adequate RBC production supports cellular function, while deficiencies can lead to anemia and associated symptoms.
Possible Side Effects
Headache is pain in the head ranging from mild to severe, potentially with nausea, light/sound sensitivity, or dizziness. It can be caused by tension, dehydration, stress, or medication side effects, and persistent headaches require medical evaluation.
Acne is a common skin condition involving comedones, papules, pustules, and nodules caused by factors like excess sebum, clogged follicles, inflammation, and bacteria. Severity ranges from mild breakouts to severe inflammation and scarring.
Diarrhea involves frequent, loose stools due to infections, medications, or underlying conditions, leading to potential dehydration and electrolyte imbalance. Symptoms include abdominal cramps, bloating and nausea.
Nausea is an unpleasant sensation of stomach unease, often preceding vomiting, caused by various factors like medications or infections. Prolonged nausea can lead to complications like dehydration.
Scientific Evidence
Martens, J. H., Barg, H., Warren, M. J., & Jahn, D. (2002). Microbial production of vitamin B12. Applied microbiology and biotechnology, 58(3), 275-285; Obeid, R., Fedosov, S. N., & Nexø, E. (2007). Cobalamin coenzyme forms are not likely to be superior to cyano- and hydroxocobalamin in prevention or treatment of cobalamin deficiency. Molecular nutrition & food research, 51(10), 1321-1328; Kumar, N., et al. (2022). Vitamin B12 in Peripheral Neuropathy: A Narrative Review. Cureus, 14(3), e23064.
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