Interaction with Lab Tests

Biotin supplementation can interfere with lab tests, especially thyroid function tests and troponin assays, potentially causing falsely high or low results. Inform healthcare providers about biotin intake before testing.

Biotin, a B-vitamin often taken as a dietary supplement, can significantly interfere with the accuracy of certain laboratory tests. This interference is particularly problematic with immunoassays used to measure thyroid function (e.g., TSH, T4, T3) and cardiac biomarkers like troponin. Biotin can lead to falsely elevated or falsely decreased results, depending on the assay methodology. These inaccurate results can lead to misdiagnosis, inappropriate treatment, and unnecessary anxiety for patients. The magnitude of the interference depends on the biotin dose and the specific assay used by the lab.