Liver Toxicity

Liver toxicity (hepatotoxicity) is liver damage induced by substances such as drugs or chemicals, potentially leading to liver failure. Symptoms include jaundice, abdominal pain, and fatigue, with severe cases possibly fatal.

Liver toxicity, also known as hepatotoxicity, refers to liver injury caused by exposure to drugs, chemicals, or other substances. It can manifest in various forms, ranging from mild elevations in liver enzymes (asymptomatic) to acute liver failure. Mechanisms include direct cellular damage, disruption of metabolic pathways, immune-mediated injury, and cholestasis (impaired bile flow). Symptoms may include jaundice (yellowing of the skin and eyes), abdominal pain, nausea, vomiting, fatigue, dark urine, and pale stools. Severe cases can lead to encephalopathy (brain dysfunction) and death.