Muscle Weakness

Muscle weakness (myasthenia) is a reduction in muscle force, leading to difficulty with movement. With GABA supplementation, it may result from excessive GABAergic inhibition, impacting motor neuron function.

Muscle weakness, also known as myasthenia, refers to a reduction in the force that muscles can exert, leading to difficulty with movements such as lifting objects, walking, or maintaining posture. In the context of GABA supplementation, it's hypothesized that this weakness could arise from excessive GABAergic inhibition at the neuromuscular junction or within the central nervous system, impacting motor neuron function. Symptoms may include generalized fatigue, difficulty with repetitive movements, and a feeling of heaviness in the limbs. The precise mechanism by which GABA supplementation could induce muscle weakness is not fully understood and warrants further research. Factors such as individual sensitivity to GABA, pre-existing neuromuscular conditions, and concurrent use of other medications affecting muscle function may influence the likelihood and severity of this side effect.