Teratogenic effects during pregnancy

High doses of retinyl palmitate during pregnancy can cause birth defects in the developing fetus. Pregnant women should avoid exceeding the recommended daily allowance of vitamin A to minimize this risk.

Teratogenic effects during pregnancy refer to the potential for high doses of retinyl palmitate (a form of vitamin A) to cause birth defects in the developing fetus. These defects can range in severity and may include malformations of the heart, brain, face, and limbs. Excessive intake of vitamin A during pregnancy, particularly in the first trimester, is associated with an increased risk of these adverse outcomes. The exact mechanisms by which retinyl palmitate induces teratogenicity are complex but likely involve disruption of normal developmental processes.