Alpha-GPC is a choline compound that may improve cognitive function and athletic power by increasing acetylcholine.
Alpha-GPC (L-Alpha glycerylphosphorylcholine) is a choline-containing phospholipid acting as a precursor to acetylcholine, a critical neurotransmitter for cognitive functions. Synthesized from phosphatidylcholine, commonly derived from soy or sunflower lecithin, it is marketed as a nootropic supplement. While proposed benefits include cognitive and athletic performance enhancement, as well as neurological recovery, scientific evidence supporting these claims is moderate. Common dosages range from 300-600mg daily. Side effects are generally mild and may include heartburn, headaches, and dizziness.
Key Information
Inside Body Harmful Score
Common Dosage
300-600mg daily
Source Type
hybrid
Production Process
Alpha-GPC is produced through chemical synthesis from phosphatidylcholine, typically derived from soy or sunflower lecithin.
Use Type
Inside BodyPotential Benefits
Enhances mental processes involved in thinking, learning, and remembering, including memory, attention, focus, and processing speed. Benefits range from improved mental clarity to significant enhancements in cognitive abilities, especially in those with cognitive decline.
Power output measures the rate of work done. Improving it leads to better athletic performance, increased strength, and improved functional abilities.
Cognitive enhancement improves mental performance by boosting memory, attention, and processing speed. It works by promoting neuronal health and protecting against cognitive decline.
Alpha-GPC may enhance athletic performance by increasing power output and improving neuromuscular efficiency. It may also stimulate growth hormone secretion, aiding in muscle growth and recovery.
Alpha-GPC may improve stroke recovery by increasing acetylcholine levels, enhancing neuronal plasticity, and aiding in the repair of damaged neuronal structures. It potentially facilitates the brain's ability to reorganize and form new connections after a stroke.
Alpha-GPC may boost athletic power output by increasing acetylcholine levels, enhancing neuromuscular function and muscle contractions. This could lead to improved performance in activities requiring strength and power.
Possible Side Effects
Dizziness is a sensation of lightheadedness, unsteadiness, or vertigo that can arise from multiple causes. It can lead to falls or loss of consciousness in some cases.
Insomnia is a sleep disorder involving difficulty falling or staying asleep, leading to non-restorative sleep. It can be triggered by various factors and can result in daytime fatigue and impaired cognitive function.
Headache is pain in the head ranging from mild to severe, potentially with nausea, light/sound sensitivity, or dizziness. It can be caused by tension, dehydration, stress, or medication side effects, and persistent headaches require medical evaluation.
Heartburn is a burning pain in the chest caused by stomach acid reflux into the esophagus. It can be triggered by various factors, including diet, lifestyle, and certain medications.
Scientific Evidence
PMID: 12637119, PMID: 28165861, PMID: 24515857, Examine.com Alpha-GPC entry
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