Alpha-lipoic acid (ALA) is a versatile antioxidant and metabolic enhancer crucial for energy production and protection against oxidative stress due to its unique water and fat solubility.
Alpha-lipoic acid (ALA), also known as thioctic acid, is a naturally occurring compound that serves as a potent antioxidant in the body. It plays a crucial role in energy production within the mitochondria, helping to convert glucose into usable energy. ALA is unique because it is both water-soluble and fat-soluble, allowing it to function in various parts of the body. It has been investigated for its potential benefits in managing blood sugar, reducing oxidative stress, and supporting nerve health.
Key Information
Inside Body Harmful Score
Common Dosage
100-600mg daily (oral); Variable concentration in topical applications
Source Type
Naturally occurring (in plants and animals); also produced synthetically.
Production Process
Synthesized chemically through various methods, often involving the reaction of a dithiol with a carboxylic acid derivative.
Use Type
Inside BodyClassification & Quality
Dietary Category
Specialty Compounds
The type of dietary ingredient this is
Primary Category
Alpha-lipoic acid
Efficacy Tier
Tier 1: High Bioavailability
"Body-ready" or active forms. Bypasses conversion steps. Maximum absorption, lowest waste.
Functions as a potent antioxidant without requiring significant conversion steps. Readily absorbed and utilized by the body.
Conversion Steps
0
Body-ready form
Number of metabolic steps the body needs to convert this ingredient into its usable form
Potential Benefits
Antioxidant support protects cells from damage by neutralizing free radicals, supporting immune function, and reducing inflammation. It contributes to overall health and may reduce the risk of chronic diseases.
Blood sugar control maintains blood glucose levels within a healthy range, preventing hyperglycemia and hypoglycemia. This involves insulin regulation, glucose uptake, and liver glucose production, crucial for preventing conditions like type 2 diabetes.
Protects cells from damage by neutralizing free radicals.
Possible Side Effects
Hypoglycemia is a condition of low blood sugar, potentially caused by alpha-lipoic acid (ALA) enhancing the effects of blood sugar-lowering medications. It can cause symptoms ranging from shakiness to severe neurological issues.
Scientific Evidence
Extensive research supports ALA's role as an antioxidant and its potential in managing diabetic neuropathy and improving insulin sensitivity. Studies also explore its effects on cardiovascular health and cognitive function. Evidence levels vary, with some applications showing stronger support than others.
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