About MSM

Methylsulfonylmethane (MSM) is a synthetic organosulfur compound used as a dietary supplement. It is believed to offer benefits primarily related to reducing inflammation and oxidative stress, including potential support for joint health, muscle recovery, allergy relief, and skin health. While generally safe, gastrointestinal upset and headache are possible side effects. Research supports some benefits, particularly for joint health and muscle recovery, but further studies are needed to confirm efficacy and fully elucidate mechanisms of action across all purported health applications.

Key Information

Category
Specialty Compounds
Use Type
Inside Body

Compare All Forms

Compare different forms of MSM by bioavailability, conversion rates, and active ingredient content:

Form Tier Steps MSM
(mg)
Bioavailability Action
MSM (Methylsulfonylmethane) Tier 1 0 — High bioavailability form. Body-ready, bypasses conversion steps. Maximum absorption, lowest waste. View →

Scientific Evidence

Key research areas include studies on osteoarthritis (e.g., randomized controlled trials assessing pain reduction and function improvement), exercise-induced muscle damage (assessing markers of muscle damage and recovery), allergy symptom relief (investigating its role in histamine response), and skin health (examining its impact on collagen production and antioxidant capacity). Specific studies can be found in PubMed and Google Scholar using keywords like "MSM osteoarthritis," "MSM muscle recovery," "MSM allergy," and "MSM skin health."