Epidermal Growth Factor (EGF) is a naturally occurring protein that stimulates cell growth, proliferation, and differentiation by binding to its receptor, EGFR. It plays a crucial role in wound healin...
Epidermal Growth Factor (EGF) is a naturally occurring protein that stimulates cell growth, proliferation, and differentiation by binding to its receptor, EGFR. It plays a crucial role in wound healing, tissue repair, and skin rejuvenation. In cosmetic applications, it's often used to reduce wrinkles, improve skin texture, and accelerate healing. In medical contexts, it may aid in treating burns, ulcers, and other skin injuries. Different forms exist, including recombinant human EGF (rhEGF) used in topical applications.
Key Information
Outside Body Harmful Score
Common Dosage
Dosage varies widely depending on the product and intended use. Topical applications often contain EGF concentrations ranging from 0.001% to 0.1%. Injectable dosages are determined by a healthcare professional.
Source Type
natural
Production Process
EGF is often produced through recombinant DNA technology, where the human EGF gene is inserted into a host organism (e.g., bacteria or yeast) that then synthesizes the protein. The protein is then purified and formulated for specific applications.
Use Type
Outside BodyPotential Benefits
Accelerates and supports the body's natural wound repair processes. This includes reducing inflammation, promoting collagen synthesis, increasing cell proliferation, and facilitating angiogenesis, leading to faster wound closure, reduced scarring, and decreased infection risk.
Skin rejuvenation improves skin health and appearance by reducing wrinkles, improving texture and tone, addressing discoloration, and treating acne. It works by stimulating collagen production, increasing cell turnover, improving hydration, and reducing inflammation.
Possible Side Effects
Theoretical concerns exist that topical EGF could stimulate the growth of pre-existing cancerous cells. This risk is largely unproven for cosmetic use but warrants caution.
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