S-Acetyl Glutathione is a bioavailable form of glutathione designed to enhance antioxidant, detoxification, and immune support by boosting intracellular glutathione levels. The acetyl group protects g...
S-Acetyl Glutathione is a bioavailable form of glutathione designed to enhance antioxidant, detoxification, and immune support by boosting intracellular glutathione levels. The acetyl group protects glutathione from breakdown in the gut, improving absorption compared to standard glutathione. While generally well-tolerated, potential side effects such as mild gastrointestinal upset and allergic reactions should be considered. Further research is needed to fully elucidate its efficacy and safety profile.
Key Information
Inside Body Harmful Score
Common Dosage
100-500mg daily
Source Type
synthetic
Production Process
Glutathione is acetylated with an acetyl group at the sulfur atom. This modification protects it from degradation in the gut, enhancing absorption and bioavailability compared to standard glutathione.
Use Type
Inside BodyPotential Benefits
Antioxidant support protects cells from damage by neutralizing free radicals, supporting immune function, and reducing inflammation. It contributes to overall health and may reduce the risk of chronic diseases.
Zinc supports the immune system by enhancing immune cell activity, reducing infection risk, and modulating inflammatory responses. Supplementation is particularly beneficial for individuals with zinc deficiencies, helping to restore optimal zinc levels and bolster immune response.
S-Acetyl Glutathione improves glutathione levels by protecting it from gut degradation, facilitating absorption into cells. Once inside the cell, the acetyl group is removed, freeing glutathione to perform its antioxidant and detoxification functions.
S-Acetyl Glutathione may support detoxification by increasing glutathione levels, which is crucial for the liver's ability to process and eliminate toxins and free radicals.
Possible Side Effects
Gastrointestinal upset involves a variety of digestive symptoms like nausea, diarrhea, and abdominal pain. It can range from mild discomfort to severe pain and may indicate an underlying condition if persistent.
Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.
Scientific Evidence
Richie JP Jr, et al. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr. 2015;54(2):251-63. ; Sinha R, et al. Oral glutathione increases tissue glutathione in vivo: a pilot study. J Clin Biochem Nutr. 2018;62(1):78-84. ; Some manufacturers may have proprietary studies.
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