Methylfolate

Inside Body
Inside: Harmless

Key Information

Inside Body Harmful Score

Harmless

Use Type

Inside Body

Potential Benefits

Methylfolate, the active form of folate, is directly utilized by the body, bypassing enzymatic conversion. This is especially beneficial for individuals with MTHFR gene mutations, improving overall folate status.

3/5

Adequate folate intake, especially methylfolate, during pregnancy prevents neural tube defects by supporting healthy cell division and DNA synthesis in the developing fetus. This reduces the risk of conditions like spina bifida.

4/5

Methylfolate supports the production of neurotransmitters crucial for mood and cognition. Supplementation may improve mood and cognitive function, especially in individuals with depression or cognitive decline.

3/5

Methylfolate reduces homocysteine levels by converting it back into methionine within the methionine cycle. Elevated homocysteine is linked to cardiovascular and other health risks.

4/5

Possible Side Effects

Anxiety/Irritability

Methylfolate may cause anxiety or irritability in sensitive individuals due to its effect on neurotransmitter levels. Symptoms can range from mild restlessness to more pronounced mood disturbances.

low

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